Transient focal neurologic deficits complicating interleukin-2 therapy.

Bernard, J T; Ameriso, S; Kempf, R A; Rosen, P; Mitchell, M S; Fisher, M · Neurology · 1990

case_report · Level V

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Abstract

We report 2 patients with transient, focal, repetitive, stereotyped episodes of neurologic deficits during treatment with interleukin-2. One patient had recurrent monocular blindness, while the 2nd had recurrent homonymous quadrantanopia. We suggest that these attacks are provoked by endothelial cell activation induced by interleukin-2.

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