A new diagnostic approach to the Dubin-Johnson syndrome.
case_report · Level V
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Abstract
Dubin-Johnson syndrome (DJS), a congenital metabolic disorder of bilirubin excretion, was classically diagnosed by the bromsulfalein (BSP) curve and needle hepatic biopsy methods. We present three cases of DJS and propose a new diagnostic approach which could conceivably become a substitute for more aggressive techniques. The results of the 24-h urine coproporphyrin determination and 99mTc-Disofenin scintigraphy gave, together, enough data for an accurate diagnosis.
Medical subject headings
- Imino Acids
- Jaundice, Chronic Idiopathic
- Organotechnetium Compounds