Acute otitis media replacement and recurrence in the Finnish otitis media vaccine trial.
rct · Level II
Where this comes from
- Record sourced from PubMed, PMID 22972864.
- Also identified by DOI 10.1093/cid/cis799.
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Abstract
We reanalyzed the 7-valent pneumococcal conjugate vaccine trial FinOM for prevention of acute otitis media (AOM), with a focus on disease replacement due to other pathogens and AOM recurrence. We found evidence of replacement disease occurring early during the trial follow-up and little vaccine impact on recurrent overall AOM episodes.
Medical subject headings
- Otitis Media
- Pneumococcal Vaccines