Adipose tissue-derived mesenchymal stem cells: a fat chance of curing kidney disease?
Level V
Where this comes from
- Record sourced from PubMed, PMID 22975993.
- Also identified by DOI 10.1038/ki.2012.158 and PMC identifier 3445292.
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Abstract
Many kidney diseases are associated with inflammation and altered immune response. Mesenchymal stem cells (MSCs) are known for their anti-inflammatory properties and immune modulation. Demonstration that the phenotype and immunosuppressive ability of adipose tissue-derived MSCs are not affected by human kidney disease or uremic serum might have clinical significance if autologous adipose tissue-derived MSCs can be tested to prove their long-term safety and efficacy in treating kidney disease.
Medical subject headings
- Adipose Tissue
- Kidney Diseases
- Mesenchymal Stem Cells