Racial disparities in diabetic complications in an underinsured population.

Wang, Yujie; Katzmarzyk, Peter T; Horswell, Ronald; Li, Wei; Xiao, Ke; Besse, Jay; Xie, Wenting; Johnson, Jolene et al. · J Clin Endocrinol Metab · 2012

retrospective_cohort · Level III

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Abstract

It is unclear whether there is a racial difference in the incidence of diabetic complications in underinsured populations. The objective of the study was to investigate racial disparities in the incidence of diabetic complications within the Louisiana State University (LSU) Hospital System. This study (1997-2009) was conducted on a diabetic cohort enrolled in the LSU Hospital-Based Longitudinal Study. The cohort included 16,808 non-Hispanic white men, 21,983 non-Hispanic white women, 20,621 African-American men, and 33,753 African-American women who were 30-96 yr of age and had a mean value of family income of $9641/yr at baseline. The study cohort had a mean follow-up of 4.4 years. The age- and sex-adjusted incidence rates and 95% confidence intervals of end-stage renal disease (ESRD), coronary heart disease (CHD), heart failure (HF), and stroke for white diabetic patients were 15.1 (14.3-15.8), 80.9 (78.9-82.9), 48.0 (46.6-49.4), and 21.4 (20.5-22.2) per 1000 person-years, respectively. Compared with white diabetic patients, African-American diabetic patients experienced higher incident rates of ESRD [17.3 (16.6-18.0)] and lower rates of CHD [47.5 (46.3-48.6)], HF [40.7 (39.6-41.8)], and stroke [19.1 (18.4-19.9)]. Female diabetic patients had lower rates of the four complications than male diabetic patients. Results of the Cox proportional hazard models confirmed sex and race disparity observed in the age-adjusted incidence rates. Despite equal access to care, diabetic African-Americans have a higher risk of ESRD than their white counterparts, whereas diabetic whites have higher risks of CHD, HF, and stroke than their African-American counterparts.

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