Diabetic β Cells: To Be or Not To Be?
editorial · Level V
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- Record sourced from PubMed, PMID 22980973.
- Also identified by DOI 10.1016/j.cell.2012.08.021 and PMC identifier 4692270.
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Abstract
β cell dysfunction with subsequent apoptosis is considered a significant contributor to the development of type 2 diabetes. Emerging data from Talchai et al. suggest β cell dedifferentiation as an alternative mechanism of insulin insufficiency that might be more amenable to intervention in at least a subset of patients.