Neuroscience. The emerging biology of autism spectrum disorders.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22984058.
- Also identified by DOI 10.1126/science.1224989 and PMC identifier 3657753.
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Abstract
Autism spectrum disorders (ASD) are a genetically and phenotypically heterogeneous group of syndromes defined by fundamental impairments in social reciprocity and language development accompanied by highly restrictive interests and/or repetitive behaviors. Recent advances in genetics, genomics, developmental neurobiology, systems biology, monogenic neurodevelopment syndromes, and induced pluripotent stem cells (iPSC) are now offering remarkable insights into their etiologies and converging to provide a clear and immediate path forward from the bench to the bedside.
Medical subject headings
- Child Development Disorders, Pervasive
- Gene Expression Regulation, Developmental
- Neocortex