Molecular catch and release: controlled delivery using optical trapping with light-responsive liposomes.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 22987599.
- Also identified by DOI 10.1002/adma.201202180 and PMC identifier 4048806.
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Abstract
Gold-coated liposomes are maneuvered using an optical trap to achieve precise delivery of encapsulated molecular cargo. Movement and payload release from these plasmon resonant nanocapsules are independently controlled using a pulsed trapping beam. This technology enables in vitro delivery of a payload to a selected cell and may be applied to the interrogation of individual cells within their biological microenvironment.
Medical subject headings
- Drug Delivery Systems
- Light
- Liposomes
- Optical Tweezers