Pancytopenia in systemic lupus erythematosus related to azathioprine.
case_report · Level V
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Abstract
A patient with systemic lupus erythematosus (SLE) developed pancytopenia when azathioprine (first 2.0 mg kg-1 day-1, then 2.5 mg kg-1 day-1) was added to prednisone for active SLE. This unusual toxic effect of azathioprine occurred during the reduction of corticosteroid dosage. After discontinuation of azathioprine, clinical and haematological recovery occurred.
Medical subject headings
- Lupus Erythematosus, Systemic
- Pancytopenia