Expanding roles for SREBP in metabolism.
review · Level V
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- Record sourced from PubMed, PMID 23000402.
- Also identified by DOI 10.1016/j.cmet.2012.09.002 and PMC identifier 3466394.
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Abstract
Sterol regulatory element-binding protein (SREBP) transcription factors regulate cellular lipogenesis and lipid homeostasis. Recent studies reveal expanding roles for SREBPs with the description of new regulatory mechanisms, the identification of unexpected transcriptional targets, and the discovery of functions for SREBPs in type II diabetes, cancer, immunity, neuroprotection, and autophagy.
Medical subject headings
- Sterol Regulatory Element Binding Proteins