Amyotrophic lateral sclerosis in a patient with fragile X syndrome.

Desai, H B; Donat, J; Shokeir, M H; Munoz, D G · Neurology · 1990

case_report · Level V

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Abstract

Fragile X syndrome is a common cause of mental retardation. We report the clinical and pathologic features of a patient with fragile X syndrome who developed amyotrophic lateral sclerosis (ALS) at a relatively young age. Although the occurrence of these 2 diseases could be a mere coincidence, the development of ALS in this patient might be related to the chromosomal aberration of fragile X syndrome.

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