Platelet antigens in varicella associated thrombocytopenia.
case_series · Level IV
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- Record sourced from PubMed, PMID 2301979.
- Also identified by PMC identifier 1792405.
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Abstract
Serum IgG or, predominantly, IgM antibody binding to electrophoretically separated normal platelet membrane protein antigens were detected by immunoblotting in five children with thrombocytopenia associated with varicella. Glycoproteins GPIb, GPIIb, GPIIIa, and other 25-260 kilodalton (kDa) proteins were identified as target antigens, suggesting a transient autoimmune mechanism causing the thrombocytopenia.
Medical subject headings
- Antigens, Surface
- Chickenpox
- Platelet Membrane Glycoproteins
- Thrombocytopenia