A molecular link tethering neuronal responses with the past.
basic_science · Level V
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- Record sourced from PubMed, PMID 23021210.
- Also identified by DOI 10.1016/j.cell.2012.09.008.
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Abstract
Neurons need to alter their response to a given stimulus over time in order for the animal to modify its behavior within a changing environment. Chen et al. now demonstrate that neuronal structure and function are altered coordinately by the history of the cell's activity through an unexpected molecular pathway.