Ultralow voltage, OTFT-based sensor for label-free DNA detection.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23027594.
- Also identified by DOI 10.1002/adma.201202996.
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Abstract
An organic ultralow voltage field effect transistor for DNA hybridization detection is presented. The transduction mechanism is based on a field-effect modulation due to the electrical charge of the oligonucleotides, so label-free detection can be performed. The device shows a sub-nanometer detection limit and unprecedented selectivity with respect to single nucleotide polymorphism.
Medical subject headings
- DNA
- Electricity
- Organic Chemicals
- Transistors, Electronic