Cutaneous extramedullary hematopoiesis with a preponderance of atypical megakaryocytes in myelofibrosis.

Schofield, J K; Shun, J L; Cerio, R; Grice, K · J Am Acad Dermatol · 1990

case_report · Level V

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Abstract

Extramedullary hematopoiesis was found in the cutaneous papulonodular eruption of a 72-year-old man with myelofibrosis. This is the first reported case to show a preponderance of atypical megakaryocytes in skin lesions. The patient was also unusual in that he had marked generalized lymphadenopathy. The skin lesions almost disappeared after treatment with hydroxyurea.

Medical subject headings