The unfolded protein response: a multifaceted regulator of lipid and lipoprotein metabolism.
Where this comes from
- Record sourced from PubMed, PMID 23040063.
- Also identified by DOI 10.1016/j.cmet.2012.09.008.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Elevated levels of circulating lipids are the major cause of cardiovascular disease, but beneficial outcomes might be realized by targeting lipid carriers. Two papers in this issue of Cell Metabolism (So et al., 2012; Wang et al., 2012) demonstrate how modulation of one arm of the unfolded protein response can decrease plasma levels of VLDL particles and their associated lipids.