Asymmetric stem cell division: precision for robustness.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 23040475.
- Also identified by DOI 10.1016/j.stem.2012.09.003.
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Abstract
Asymmetric cell division (ACD) produces two daughter cells with distinct fates or characteristics. Many adult stem cells use ACD as a means of maintaining stem cell number and thus tissue homeostasis. Here, we review recent progress on ACD, discussing conservation between stem and non-stem cell systems, molecular mechanisms, and the biological meaning of ACD.
Medical subject headings
- Adult Stem Cells
- Asymmetric Cell Division