Dual-imaging enabled cancer-targeting nanoparticles.
basic_science · Level V
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- Record sourced from PubMed, PMID 23061030.
- Also identified by PMC identifier 3466609.
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Abstract
The development of dual-imaging enabled cancer-targeting nanoparticles (DICT-NPs) is reported based on newly developed biodegradable photoluminescent polymers and superparamagnetic iron oxide nanoparticles. DICT-NPs possess capabilities of dual-imaging (magnetic resonance imaging and optical imaging), magnetic targeting, and potentially selective targeting for cancer cells. The development of DICT-NPs address the concerns in dual-imaging nanoparticles where photobleaching organic dyes and cytotoxic quantum dots are usually adopted.
Medical subject headings
- Magnetic Resonance Imaging
- Microscopy, Fluorescence
- Nanoparticles
- Prostatic Neoplasms
- Subtraction Technique