Amazing IL-9: revealing a new function for an "old" cytokine.
Level V
Where this comes from
- Record sourced from PubMed, PMID 23064368.
- Also identified by DOI 10.1172/JCI65929 and PMC identifier 3484464.
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Abstract
The incidence of melanoma - the most aggressive form of skin cancer - is dramatically increasing, while the development of innovative therapeutic strategies continues to be challenging, especially due to a lack of knowledge about the molecular mechanisms underlying melanoma progression as well as antitumor immunity. In this issue of the JCI, Yong Lu and colleagues report a central role for Th9 cells in antitumor immunity.
Medical subject headings
- CD8-Positive T-Lymphocytes
- Immunity, Cellular
- Interleukin-9
- Lung Neoplasms
- Melanoma
- T-Lymphocytes, Helper-Inducer