Surface-immobilized monolayers of conjugated oligomers as a platform for fluorescent sensors design: the effect of exciton delocalization on chemosensing performance.

Imsick, Brian G; Acharya, Jiba Raj; Nesterov, Evgueni E · Adv Mater · 2013

basic_science · Level V

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Abstract

Surface-immobilized monolayers of fluorescent molecular sensors consisting of a short conjugated oligo(p-phenylene ethynylene) core end-capped with an acceptor fluorophore (analyte receptor) display significant signal amplification due to enhanced intermolecular energy transfer within the monolayer. This general phenomenon offers a superior platform for designing ratiometric fluorescent sensors. An example of how this can be used to convert a narrow-range threshold fluorescent pH indicator (fluorescein) to a broad-range ratiometric fluorescent chemosensor is described.