Calcific aortic stenosis in twins: a clue to its pathogenesis?

Lewis, N P; Henderson, A H · Eur Heart J · 1990

case_report · Level V

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Abstract

A pair of identical twins presented almost simultaneously at age 62 years with calcific aortic stenosis requiring surgery, one with bicuspid and one with tricuspid aortic valve. This suggests that bicuspid morphology may perhaps not be the cause, but may be a genetically linked marker of an inherited predisposition to calcific stenosis.

Medical subject headings