A simple packed bed device for antibody labelled rare cell capture from whole blood.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23079718.
- Also identified by DOI 10.1039/c2lc41048f.
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Abstract
We have developed a system to isolate rare cells from whole blood using commercially available components and simple microfluidics. We characterized the capture of MCF-7 cells spiked into whole human blood using this system to demonstrate that enrichment and enumeration studies give results similar to in situ surface-modified devices while reducing fabrication and operation complexity.
Medical subject headings
- Antibodies
- Cell Separation
- Microfluidic Analytical Techniques
- Neoplastic Cells, Circulating