The index case for the fungal meningitis outbreak in the United States.

Pettit, April C; Kropski, Jonathan A; Castilho, Jessica L; Schmitz, Jonathan E; Rauch, Carol A; Mobley, Bret C; Wang, Xuan J; Spires, Steven S et al. · N Engl J Med · 2012

case_report · Level V

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Abstract

Persistent neutrophilic meningitis presents a diagnostic challenge, because the differential diagnosis is broad and includes atypical infectious causes. We describe a case of persistent neutrophilic meningitis due to Aspergillus fumigatus in an immunocompetent man who had no evidence of sinopulmonary or cutaneous disease. An epidural glucocorticoid injection was identified as a potential route of entry for this organism into the central nervous system, and the case was reported to the state health department.

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