Bone mineral density increases in HIV-infected children treated with long-term combination antiretroviral therapy.

Bunders, Madeleine J; Frinking, Olivier; Scherpbier, Henriette J; van Arnhem, Lotus A; van Eck-Smit, Berthe L; Kuijpers, Taco W; Zwinderman, Aeilko H; Reiss, Peter et al. · Clin Infect Dis · 2013

prospective_cohort · Level II

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Abstract

The long-term treatment of human immunodeficiency virus (HIV)-infected children with combination antiretroviral therapy (cART) requires assessment of potential adverse effects, such as osteoporosis. Longitudinal data on bone mineral density (BMD) in HIV-infected children showed that cumulative treatment with cART had a positive impact on BMD over time.

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