Lupus antibody tops cancer cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23100623.
- Also identified by DOI 10.1126/scitranslmed.3004955.
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Abstract
A lupus causing anti-DNA antibody penetrates living cells and targets DNA repair for therapeutic advantage in human cancer cells.
Medical subject headings
- Antibodies, Antinuclear
- Antibodies, Antinuclear/immunology
- BRCA2 Protein
- BRCA2 Protein/metabolism
- DNA Repair
- Humans
- Lupus Erythematosus, Systemic
- Lupus Erythematosus, Systemic/immunology
- Neoplasms
- Neoplasms/immunology
- Neoplasms/pathology