Pathological laughter.

Zellers, G L; Frank, M; Dougherty, J · Ann Emerg Med · 1990

case_report · Level V

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Abstract

A man experienced one hour and 40 minutes of continual, inappropriate, uncontrollable laughter. The onset was preceded by a single-inhalation exposure to an insecticide of very low toxicity. The episode was terminated by a single dose of IV diazepam. A discussion of pathological laughter, including its proposed pathophysiology, differential diagnosis, clinical relevance, and management, is presented.

Medical subject headings