A tollgate for typhoid.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23101620.
- Also identified by DOI 10.1016/j.cell.2012.10.016 and PMC identifier 6524972.
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Abstract
Humans are uniquely susceptible to typhoid fever caused by infection with Salmonella enterica serovar Typhi. Mathur et al. now report that mice lacking Toll-like receptor 11, which is absent in humans, can be lethally infected with S. Typhi, a breakthrough that promises to speed the development of better vaccines.