DropletMicroarray: facile formation of arrays of microdroplets and hydrogel micropads for cell screening applications.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23114283.
- Also identified by DOI 10.1039/c2lc40921f.
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Abstract
We describe a one-step method for creating thousands of isolated pico- to microliter-sized droplets with defined geometry and volume. Arrays of droplets are instantly formed as liquid moves along a superhydrophilic-superhydrophobic patterned surface. Bioactive molecules, nonadherent cells, or microorganisms can be trapped in the fully isolated microdroplets for high-throughput screening, or in hydrogel micropads for screening in 3D microenvironments.
Medical subject headings
- Cell Separation
- Hydrogels
- Microfluidic Analytical Techniques