Fragmentation of poly(lactic acid) nanosheets and patchwork treatment for burn wounds.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23117996.
- Also identified by DOI 10.1002/adma.201202851.
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Abstract
Freestanding poly(L-lactic acid) (PLLA) nanosheets are mass-produced by a simple combination of a spin-coating-assisted multi-layering process and a peeling technique. The resulting PLLA nanosheets are fragmented by homogenization and then reconstructed into a "patchwork" sheet on various surfaces without any adhesive reagents. The patchwork is shown to offer excellent protection against burn wound infection with Pseudomonas aeruginosa, and may therefore be an alternative to conventional burn therapy for prevention of infection.
Medical subject headings
- Burns
- Lactic Acid
- Nanostructures
- Polymers