Response to therapy following retreatment of serofast early syphilis patients with benzathine penicillin.

Seña, Arlene C; Wolff, Mark; Behets, Frieda; Van Damme, Kathleen; Martin, David H; Leone, Peter; McNeil, Linda; Hook, Edward W · Clin Infect Dis · 2013

case_series · Level IV

Where this comes from

Abstract

Persistent nontreponemal titers after treatment are common among patients with early syphilis. We retreated 82 human immunodeficiency virus-negative early syphilis participants who were serofast at 6 months using benzathine penicillin. Only 27% exhibited serological response after retreatment and after an additional 6 months of follow-up.

Medical subject headings