Ivermectin inhibits growth of Chlamydia trachomatis in epithelial cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23119027.
- Also identified by DOI 10.1371/journal.pone.0048456 and PMC identifier PMC2788228.
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Abstract
Ivermectin is currently approved for treatment of both clinical and veterinary infections by nematodes, including Onchocerca cervicalis in horses and Onchocerca volvulus in humans. However, ivermectin has never been shown to be effective against bacterial pathogens. Here we show that ivermectin also inhibits infection of epithelial cells by the bacterial pathogen, Chlamydia trachomatis, at doses that could be envisioned clinically for sexually-transmitted or ocular infections by Chlamydia.