Maps for changing landscapes: viewing epigenomic signatures through differentiation.

Bulger, Michael · Cell Stem Cell · 2012

review · Level V

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Abstract

Enormous progress has been made in identifying chromatin "signatures" that define tissue-specific transcriptional networks. Three recent studies by Rada-Iglesias et al. (2012), Wamstad et al. (2012), and Paige et al. (2012) track such signatures during cellular differentiation, revealing a richer understanding of gene regulation and providing hints of new phenomena.