No association between TGF-β1 polymorphisms and radiation-induced lung toxicity in a European cohort of lung cancer patients.

Voets, An M; Oberije, Cary; Struijk, Robin B; Reymen, Bart; De Ruyck, Kim; Thierens, Hubert; Vandecasteele, Katrien; De Neve, Wilfried et al. · Radiother Oncol · 2012

case_control · Level III

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Abstract

This study aimed at validating the previously published association between TGF-β1 single nucleotide polymorphisms and a reduced risk for radiation-induced lung toxicity. We were not able to confirm the reported association, neither using maximum dyspnea score nor after correction for baseline dyspnea score.

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