Tunable carbon nanotube/protein core-shell nanoparticles with NIR- and enzymatic-responsive cytotoxicity.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23135812.
- Also identified by DOI 10.1002/adma.201203382.
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Abstract
A unique procedure is developed to capture carbon nanotubes into closed virus-like protein cages with a controllable shell. The cross-linked shell varies in thickness within ≈10(0) -10(2) nm, and can be entirely removed by enzyme degradation. The cytotoxicity is entirely suppressed, but can be promoted again by enzymes and near-infrared light. These hybrids can be decorated with functional inorganic nanoparticles or processed into nanocomposites.
Medical subject headings
- Infrared Rays
- Nanoparticles
- Nanotubes, Carbon
- Proteins