Antibacterial strategies from the sea: polymer-bound cl-catechols for prevention of biofilm formation.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23139083.
- Also identified by DOI 10.1002/adma.201203362.
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Abstract
Inspired by the amino acid 2-chloro-4,5-dihydroxyphenylalanine (Cl-DOPA), present in the composition of the proteinaceous glue of the sandcastle worm Phragmatopoma californica, a simple strategy is presented to confer antifouling properties to polymer surfaces using (but not releasing) a bioinspired biocide. Cl-Dopamine is used to functionalize polymer materials and hydrogel films easily, to prevent biofilm formation on them.
Medical subject headings
- Anti-Bacterial Agents
- Biofilms
- Catechols
- Polymers