Treating diabetes by blocking a vascular growth factor.
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- Record sourced from PubMed, PMID 23140637.
- Also identified by DOI 10.1016/j.cmet.2012.10.015.
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Abstract
Ectopic lipid deposition in muscle and liver is associated with the pathogenesis of type II diabetes. Hagberg et al. (2012) report that targeting the vascular endothelial growth factor (VEGF)-B restores insulin sensitivity and glucose tolerance by inhibiting endothelial-to-tissue lipid transport, opening promising avenues for diabetes therapy.