Carbapenem-sparing antibiotic regimens for infections caused by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae in intensive care unit.
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 23155147.
- Also identified by DOI 10.1093/cid/cis969.
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Abstract
A carbapenem-sparing regimen of tigecycline plus gentamicin or colistin was effective for treating 24 of 26 (92%) Klebsiella pneumoniae carbapenemase-producing K. pneumoniae infectious episodes in 22 polytrauma intensive care unit patients without comorbidities. The 30-day crude mortality rate was 14%. Regimens were considered appropriate in 12% of episodes according to the Vitek 2 System and in 100% based on E-test.
Medical subject headings
- Anti-Bacterial Agents
- Bacterial Proteins
- Colistin
- Gentamicins
- Klebsiella Infections
- Klebsiella pneumoniae
- Minocycline
- beta-Lactamases