Could antiprogesterones be used as alternative cervical ripening agents?
case_series · Level IV
Where this comes from
- Record sourced from PubMed, PMID 2316569.
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Abstract
We measured the effect of a progesterone antagonist on the pregnant cervix with a custom-built cervicometer. The change in cervical diameter was studied in 11 pregnant patients after oral administration of 600 mg of RU-486. In all cases RU-486 ripened the cervix (p = 0.0007). The average increase in diameter was 13% (95% confidence limits, 10% to 16%).
Medical subject headings
- Cervix Uteri
- Mifepristone
- Progesterone