The safety of amphotericin B lipid complex in patients with prior severe intolerance to liposomal amphotericin B.

Farmakiotis, Dimitrios; Tverdek, Frank P; Kontoyiannis, Dimitrios P · Clin Infect Dis · 2013

retrospective_cohort · Level III

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Abstract

The tolerability of amphotericin B lipid complex in patients with previous severe infusion reactions to liposomal amphotericin B is unclear. We reviewed the charts of 40 such patients at a tertiary care cancer center and found that amphotericin B lipid complex administration was uneventful in 34 patients (85% [95% confidence interval, 69%-93%]).

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