Influenza epidemics and anencephaly.

Saxén, L; Holmberg, P C; Kurppa, K; Kuosma, E; Pyhälä, R · Am J Public Health · 1990

case_control · Level III

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Abstract

To explore the postulated association between maternal influenza and congenital defects of the central nervous system, 14 virologically verified epidemics in Finland, 1969-82, were studied. Mothers of 248 anencephalic children were grouped into those whose first trimester had occurred during an epidemic period and those whose pregnancy had commenced during a non-epidemic period. No significant differences in prevalence of anencephaly were noted in these groups.

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