Reducing bacterial colonization of 3-d nanofiber cell scaffolds by hierarchical assembly of microgels and an antimicrobial Peptide.

Wang, Qichen; Yu, Xiaojun; Libera, Matthew · Adv Healthc Mater · 2013

basic_science · Level V

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Abstract

The hierarchical electrostatic deposition of anionic microgels and a cationic oligopeptide throughout a PCL-chitosan nanofiber scaffold inhibits S. epidermidis colonization of the scaffold interior while promoting osteoblast adhesion, spreading, and proliferation on the scaffold surface.

Medical subject headings