A highly sensitive gold-nanoparticle-based assay for acetylcholinesterase in cerebrospinal fluid of transgenic mice with Alzheimer's disease.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23184691.
- Also identified by DOI 10.1002/adhm.201100002.
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Abstract
A highly sensitive, selective, and dual-readout (colorimetric and fluorometric) assay for acetylcholinesterase (AChE) based on Rhodamine B-modified gold nanoparticle is reported. Due to its good sensitivity and selectivity, the assay can be used for monitoring AChE levels in the cerebrospinal fluid of transgenic mice with Alzheimer's disease.
Medical subject headings
- Acetylcholinesterase
- Alzheimer Disease
- Colorimetry
- Gold
- Nanoparticles