Magnetic nanocomposite sol-gel systems for remote controlled drug release.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23184692.
- Also identified by DOI 10.1002/adhm.201100013.
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Abstract
The remote heating of iron oxide nanoparticles in an alternating magnetic field is used to drive a thermoresponsive sol-gel block copolymer, Pluronic® F-127, through the upper phase transition temperature. This phase change triggers an accelerated release rate of a model drug. Actuation and return to baseline levels are demonstrated for multiple AMF doses.
Medical subject headings
- Delayed-Action Preparations
- Ferric Compounds
- Nanoparticles
- Poloxamer