Enhanced enzymatic thermal stability and activity in functionalized mesoporous silica monitored by (31) p NMR.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23184722.
- Also identified by DOI 10.1002/adhm.201100024.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Organophosphorus hydrolase (OPH) is immobilized on ammonium-modified mesoporous silica particles. Thermal stability and activity are measured with a (31) P NMR assay of the conversion of paraoxon (toxic) to its non-toxic hydrolysis product. After immobilization, OPH is significantly more active at room temperature and retained activity even after being heated to 45 °C for 1 month.
Medical subject headings
- Aryldialkylphosphatase
- Magnetic Resonance Spectroscopy
- Silicon Dioxide