Cascaded photoinduced drug delivery to cells from multifunctional core-shell mesoporous silica.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23184746.
- Also identified by DOI 10.1002/adhm.201100033.
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Abstract
Different bioactive molecules are released into living cells from lipid-covered mesoporous silica nanoparticles. The release is triggered by light, as the particles feature covalently attached photosensitizers as membrane-opening agents. It is demonstrated that the particles achieve endosomal escape and that they release their cargo into the cytosol.
Medical subject headings
- Nanocapsules
- Photosensitizing Agents
- Protoporphyrins
- Silicon Dioxide