PEI conjugated gold nanoparticles: efficient gene carriers with visible fluorescence.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23184751.
- Also identified by DOI 10.1002/adhm.201200033.
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Abstract
Low molecular weight polyethyleneimines were conjugated onto gold nanoparticles to form Au-PEI conjugates. Au-PEI is the first reported gene carrier which has both high transfection efficiency and strong fluorescence. Au-PEI showed higher transfection efficiency and it can be used for bioimaging because it can be detected by confocal laser scanning microscopy and in vivo bioimaging system.
Medical subject headings
- Fluorescent Dyes
- Gold
- Imines
- Microscopy, Fluorescence
- Nanocapsules
- Polyethylenes
- Transfection