Biomineralization-based virus shell-engineering: towards neutralization escape and tropism expansion.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23184775.
- Also identified by DOI 10.1002/adhm.201200034.
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Abstract
Biomineralization-based virus shell-engineering (BVSE) is a potential surface modification strategy to afford a biocompatible and biodegradable calcium phosphate (CaPi) shell onto single virus, allowing development of Trojan virus with enhanced infection, expanded tropism and neutralization escape, which open up the multiple applications of virus in biomedicines and materials.
Medical subject headings
- Adenoviridae
- Calcium Phosphates
- Capsid
- Genetic Engineering