Rational molecular design of complementary self-assembling peptide hydrogels.

Kyle, Stuart; Felton, Susan H; McPherson, Michael J; Aggeli, Amalia; Ingham, Eileen · Adv Healthc Mater · 2012

basic_science · Level V

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Abstract

Rational molecular design of self- assembling peptide-based materials that spontaneously form self-supporting hydrogels shows potential in many healthcare applications. Binary peptides based on complementary charged sequences are developed, and the use of biophysical analysis and cell-based studies highlights that the charged interactions can influence the properties of peptide materials and ultimately affect biomaterial applications.

Medical subject headings