Hybrid conducting polymer-hydrogel conduits for axonal growth and neural tissue engineering.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 23184828.
- Also identified by DOI 10.1002/adhm.201200182.
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Abstract
Successfully and efficiently bridging peripheral nerve gaps without the use of autografts is a substantial clinical advance for peripheral nerve reconstructions. Novel templating methods for the fabrication of conductive hydrogel guidance channels for axonal regeneration are designed and developed. PEDOT is electrodeposited inside the lumen to create fully coated-PEDOT agarose conduits and partially coated-PEDOT agarose conduits.
Medical subject headings
- Axons
- Bridged Bicyclo Compounds, Heterocyclic
- Hydrogels
- Nerve Regeneration
- Peroneal Neuropathies
- Polymers
- Tissue Scaffolds