CCK-8S inhibits L-dopa-induced dyskinesias in parkinsonian squirrel monkeys.
basic_science · Level V
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- Record sourced from PubMed, PMID 2320253.
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Abstract
Systemic administration of CCK-8S (1 or 10 micrograms/kg IP) markedly inhibited L-dopa-induced dyskinesias in parkinsonian monkeys, but did not interfere with locomotor stimulation by L-dopa. CCK analogues may be useful antidyskinetic agents for improved control of Parkinson's disease.
Medical subject headings
- Dyskinesia, Drug-Induced
- Levodopa
- Parkinson Disease, Secondary
- Sincalide